Optimising cardiovascular risk management early in the diabetes disease trajectory

Type 2 diabetes increases an individual’s risk of Cardiovascular Disease (CVD). Trials have demonstrated the long term macro-vascular benefits of lowering glucose, as well as other CVD risk factors, in populations with established diabetes.

Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen-detected diabetes? Results from the ADDITION-Europe cluster randomized trial.

AIMS: Little is known about the long-term effects of intensive multifactorial treatment early in the diabetes disease trajectory. In the absence of long-term data on hard outcomes, we described change in 10-year modelled cardiovascular risk in the 5 …

Effect of early intensive multifactorial therapy on modelled coronary heart disease risk in individuals with diabetes detected by screening: ADDITION-Europe, a randomised trial